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12/9/2025

Why Informed Consent Fails at Menopause(and how to fix it)

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Summary: How well women feel during menopause depends less on their symptoms and more on their belief that they can manage those symptoms—thus it matters a lot whether doctors help or hurt that belief. Doctors fail women in two ways: using old, outdated information or distrusting good science. Both result in women getting the wrong advice. The fix: women need to build confidence in managing their health and spot good medical care, while doctors need to learn how to tell solid research from weak research. Right now, the system creates a difficult situation, where poor care impairs women's confidence, women’s symptoms get more severe, and leave women with fewer options in life, which makes it harder to design a satisfying life after menopause.Why Informed Consent Fails at Menopause

Quick Takes

#1: The Self-Efficacy MultiplierWomen with high self-efficacy (confidence that they can successfully manage a specific challenge) cope better with menopausal symptoms regardless of severity. But this means that women who struggle the most with self-efficacy will often find themselves seeking help. When they encounter poor medical care, two harms occur: self-efficacy erodes further AND symptoms constrain life more (work, relationships, functioning). Both worsen symptoms. Physicians aren’t just failing to help—they may cause harm by weakening the resource women need most.

#2: Two Paths to Wrong Information
Physicians fail women by: (1) getting stuck on outdated warnings from old hormone formulations, OR (2) rejecting rigorous trials as untrustworthy while focusing on observational studies and animal models as equally valid. Both betray trust. Example: observational studies suggest MHT clearly protects heart and brain, but randomized trials (which remove selection bias) only prove bone benefits. Being "pro-woman" requires engaging with best science, not abandoning rigor.

#3: Informed Consent Needs Both
True informed consent requires scientific accuracy AND respect for autonomy. 
  • Accuracy without respect = paternalism = no informed consent. 
  • Respect without accuracy = informed consent also becomes impossible. 
Women must build self-efficacy and learn to spot quality care. Physicians must develop research literacy, update knowledge regularly, and individualize recommendations. We have work to do.

Favorite Finds

Building Self-Efficacy

There are evidence‑based ways to increase self‑efficacy, including in peri‑ and postmenopausal women. Some interventions have used counseling (Karimlou et al, 2017) or educational sessions (Khandehroo et al, 2025) (Magistro et al, 2025).

Bandura (1977) postulated the existence of 4 sources of self-efficacy, including mastery experiences (choosing a small goal and succeeding), vicarious experiences, verbal persuasion with concrete support, and managing physiological and emotional arousal.


Programs are available in many communities, for example in the Bay Area through
Stanford Medicine and Kaiser Permanente’s virtual Navigating Menopause program, and on the more integrative side, Oakland’s Menopause Wellness Circle, and the Menopausitive Workshop. I am not familiar with the details of these programs but they may be worth exploring.

Science Literacy
Anyone can learn research literacy, for example by taking this beginner “massive open online course” from Coursera: Science Literacy.
Getting what you need from a physician visit (or other provider)
  • What Patients Say, What Doctors Hear – Danielle Ofri’s book gets 4/5 stars on GoodReads.​
  • Doctors Talking with Patients/Patients Talking with Doctors – A classic text on medical communication written mainly for clinicians.
  • SHE+ Patient Advocacy guide — A totally free, very useful toolkit especially addressed to patientswho have experienced dismissal
  • Self‑Advocacy Guide for Women’s Health (Ms.Medicine) – A free (they request your email) women‑specific downloadable guide
  • My Menoplan: menopause‑focused resource that coaches women to set an agenda, prepare a symptom and question list, state visit goals clearly, and use decision tools to guide the discussion
  • Healthline has some good free advice as well.

Deep Dive

The Problem
FACT: Women couldn't vote in the US until 1920 or get credit cards in their own name until 1974. Medical research has systematically neglected women's health. These patterns of dismissing women's importance, autonomy, and concerns persist in clinical practice today.
SOLUTION: Physicians must actively recognize this historical baggage and counteract it with validation, respect, and commitment to filling knowledge gaps.


FACT: Menopause requires of women that they redefine their roles, meaning, relationships, and ways of being in the world. Women who struggle more with this transition experience more disruptive symptoms—and may find themselves needing to seek medical care.
SOLUTION: Recognize menopause as a profound life transition, not just a medical problem. The women in your office are already vulnerable and deserve support.


The Self-Efficacy Connection
FACT: Self-efficacy is your confidence that you can organize and execute a plan to reduce the impact of symptoms on your life. Women with high self-efficacy report better life satisfaction in spite of menopausal symptoms, regardless of symptom severity.
SOLUTION: Build health self-efficacy anytime—even before menopause—the belief that "what I do matters" for health outcomes changes these outcomes.


FACT: When women with lower self-efficacy encounter dismissive or poorly informed physicians, two harms occur: their self-efficacy erodes further AND their symptoms constrain their lives more (work, relationships, sexuality, functioning). Both consequences worsen symptom disruptiveness, creating a downward spiral that can be interrupted by supportive accurate care.
SOLUTION: Physicians must understand they run the risk of worsening one of the root causes of their patients’ distress—they are not just failing to help, but actively damaging women's ability to cope.


The Science Literacy Crisis
FACT: Physicians may fail women in two ways: (1) getting stuck on outdated warnings based on old hormone formulations without knowing current research, OR (2) rejecting rigorous science as untrustworthy while giving undue weight to weaker evidence like observational studies and animal models, or basic petri dish research.
SOLUTION: Real advocacy requires engaging with the best available science. Demand more rigorous research—don't abandon rigor itself. Update knowledge regularly.


FACT: Observational studies show that women who choose hormone therapy (MHT) have better outcomes—but these women also exercise more, eat better, have better healthcare access. This could be the "healthy user effect.” Randomized trials, which remove selection bias, tell a different story: MHT reliably benefits bone health, but cardiovascular and cognitive benefits aren't clearly proven. Also, for breast cancer, while bioidenticals are preferable, if MHT is started within 3 years of menopause and continued past five years, risk increases.
SOLUTION: Understand what research shows so you can be accurate with patients. Promise bone protection, not heart or brain protection. Individualize breast cancer risk assessment. Don't oversell benefits or ignore nuance. Remember to discuss the increased chance of autoimmune disease in women on MHT, and the risks of postmenopausal bleeding. Also be in a position to discuss possible benefits to oral health, skin, hair, and all the other issues MHT can affect.


What Informed Consent Requires
FACT: True informed consent requires both scientific accuracy AND respect for women's autonomy.
SOLUTION: Physicians must weigh multiple factors for each patient: age at menopause, exercise habits, bone health, breast cancer risk, family history, individual goals. Learn to read studies critically, acknowledge uncertainty, and resist oversimplification.


FACT: Most physicians lack training in drawing accurate conclusions from observational studies (selection bias) vs. randomized controlled trials (removes bias), or in clearly defining and evaluating forms of evidence.
SOLUTION: Medical education must include robust research literacy training. Physicians need to understand the consequences of study design.


Action Steps
FOR ALL PATIENTS:
  • Build health self-efficacy anytime
  • Learn what respectful care looks like: listening, validation, evidence-based recommendations
  • Know the red flags: outdated warnings, dismissiveness, inability to explain evidence


FOR PHYSICIANS:
  • Get training in research literacy—understand study design, bias, limitations
  • Examine your biases and update your knowledge regularly
  • Learn to weigh multiple factors for individualized care
  • Apply rigorous evidence evaluation to ALL treatments: hormones, antidepressants, osteoporosis medications


FOR HEALTHCARE SYSTEMS:
  • Stop making overly broad guideline statements
  • Develop better tools for individualized risk assessment
  • Support physician education in research literacy


The Bottom Line
​
FACT: Women deserve physicians who listen AND know how to read studies. They deserve respect AND accuracy. They deserve real empowerment—grounded in the best evidence, honestly interpreted, with uncertainty acknowledged.
SOLUTION: This is informed consent. Anything less is failing women while claiming to help them.

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    Dr. Myrto Ashe MD, MPH is a functional medicine family physician.

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